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・ 3-hydroxybenzoate 2-monooxygenase
・ 3-hydroxybenzoate 4-monooxygenase
・ 3-hydroxybenzoate 6-monooxygenase
・ 3-hydroxybenzoate—CoA ligase
・ 3-Hydroxybenzoic acid
・ 3-hydroxybenzyl-alcohol dehydrogenase
・ 3-Hydroxybutanal
・ 3-hydroxybutyrate dehydrogenase
・ 3-hydroxybutyryl-CoA dehydratase
・ 3-hydroxybutyryl-CoA dehydrogenase
・ 3-hydroxybutyryl-CoA epimerase
・ 3-hydroxycyclohexanone dehydrogenase
・ 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase
・ 3-Hydroxyflavone
・ 3-hydroxyindolin-2-one monooxygenase
3-hydroxyisobutyrate dehydrogenase
・ 3-Hydroxyisobutyric acid
・ 3-Hydroxyisobutyryl-CoA
・ 3-hydroxyisobutyryl-CoA hydrolase
・ 3-Hydroxykynurenine
・ 3-hydroxymethylcephem carbamoyltransferase
・ 3-Hydroxymorphinan
・ 3-Hydroxyoctanoic acid
・ 3-hydroxyoctanoyl-(acyl-carrier-protein) dehydratase
・ 3-hydroxypalmitoyl-(acyl-carrier-protein) dehydratase
・ 3-Hydroxypentanoic acid
・ 3-Hydroxyphenazepam
・ 3-hydroxyphenylacetate 6-hydroxylase
・ 3-Hydroxypicolinic acid
・ 3-hydroxypimeloyl-CoA dehydrogenase


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3-hydroxyisobutyrate dehydrogenase : ウィキペディア英語版
3-hydroxyisobutyrate dehydrogenase

In enzymology, a 3-hydroxyisobutyrate dehydrogenase () also known as β-hydroxyisobutyrate dehydrogenase or 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) is an enzyme that in humans is encoded by the ''HIBADH'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11112 )
3-Hydroxyisobutyrate dehydrogenase catalyzes the chemical reaction:
:3-hydroxy-2-methylpropanoate + NAD+ \rightleftharpoons 2-methyl-3-oxopropanoate + NADH + H+
Thus, the two substrates of this enzyme are 3-hydroxy-2-methylpropanoate and NAD+, whereas its 3 products are 2-methyl-3-oxopropanoate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase. This enzyme participates in valine, leucine and isoleucine degradation.
== Function ==

3-hydroxyisobutyrate dehydrogenase is a tetrameric mitochondrial enzyme that catalyzes the NAD+-dependent, reversible oxidation of 3-hydroxyisobutyrate, an intermediate of valine catabolism, to methylmalonate semialdehyde.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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